Leptin, Weight Insulin and how you Store Fat

What stops you eating is as much your tightening belt as leptin release at a hormonal level. Without the leptin you would release the belt and continue eating.

Leptin is a protein composed of 167 amino acids produced primarily by adipose tissue to co-ordinate metabolism of food intake and satiety. Leptin in particular signals to the brain to store or burn fat. It is the leptin released from the fat cells that tells the brain to halt the eating when you are full and increases your basal metabolic rate.

Surprisingly it is very high in fat people, squashing earlier excitement about using this protein as a weight reduction tool. It seems therefore that fat induces resistance to leptin in the same way that one develops insulin resistance as a precursor to non insulin dependent diabetic and the buffalo body remake. The similarity doesn’t stop here.

High GI food induces high leptin, therefore stopping the binge by inducing satiety almost immediately, and don’t forget it lasts over a longer period than the day of the ice cream indulgence. (About five days)
Low GI food and starvation induces low leptin but takes long to get it low enough to start you running behind the ice cream truck. You therefore will have low GI food in the system with residual high leptin levels in the blood resulting in fat breakdown and no craving.
Insulin at this very moment will be low with low glucose to induce fat loss as well.(refer to our previous blogs) It is this cycle that we exploit when we insist that you have to cheat once a week.
Match this with the natural exercise systems from our evolutionary past; bursts of high intensity exercise sandwiched between the strength or weights lifting recovery periods and you have optimum fat bursting tool without a drug.

The idea is to use medically grounded formula for your weight loss without medical language (I hope) and minimal loss of weight from your purse.
 
The similarity between IL6 and leptin is striking. This explains evolutionary role that it could have played in times of scarcity for example its role in fertility and stress. Animals don’t ovulate when stressed or starved for long. Fat outside fat cells (liver, omentum heart) is bad for your survival.
It causes inflammation in these tissues resulting and atherosclerosis at the vascular level. The induced leptin is meant to limit that inflammation.

It probably now gets clearer for an ordinary man in the street to understand how leptin resistance can be so prognostically bad for your health. It is this fat that increases your mortality to double that of control group in 10yrs.

I have previously mentioned that Jay Lo is not unhealthy. That I should probably clear before most men put me under the sword; it is Danny De Vito on the line. We need such women to look forward to tomorrow and I am not about to make lots of followers feel guilty about their daily needs.
The subject is vast; therefore we will follow up with its effect on the other systems.

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